Thank you for all the replies.  I too have run my previous versions of poser (7 and 2010) off the D: drive without any problems.  In addition, as of last summer my new computer configuration is a SSD as the C: drive and a 2 TB conventional HD as the D: drive.  The SSD drive isn't terrible big so I am trying to avoid putting too much on it besides the OS.  I will try both WandW and hborre's suggestions.