Quote - I don't think that there is any problem in using tiffs.

Well, the .tifs do seem to be turned into .jpgs in the collected textures folder, although they show up in DS4.5Pro as .tifs. But there is one folder, named temp, that has a d2.tif file in it, and that is a file that has the eye textures. Again, I no longer get the LUX Log Error message that it cannot access the temp folder. That all sounds related, somehow. At any rate, at least the image is rendering correctly now; the eyes look just fine. So, I guess I need to remember to up the Output Collect Textures options to Full Size. I went back to using the textues as is in Reality 2.5, meaning I don't have anything unchecked or set to "null." None of that was necessary.