UI's and work flow.
Even thou all the box modelers UI is defrent ,thay all work the same way just fined where the modeling tools are and your good.
There all the same tools in all the app's.
know matter what app your using your still box modeling ,mapping ,texturing ,rigging.

Some app's will click with you better then others some are faster.

Pros will have some exspearance with any app listed at CGTalk.
They probably have at least 1/2 of them.

If there determand to be a CGI Artist they tend to get at least 1 of the Fab 5 app's.

Any app The CGI tools are getting better but there still not realy all that good for characters.
If your going to compete with the pros .
You need a high end app and zBrush and even after all that you more or less half to make a machine in to a human.
Now you spend $1000's and a lot of time. What will you get for all your effort ?
You might have been better off digging threw the trash for scraps and aluminum cans.

At this point unless your a long shoot gambler it's not very feasible to make charaters.

 

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The Artist that will fight for decades to conquer their media.
Even if you never know their name ,your know their Art.
Dark Sphere Mage Vengeance