Bath salts is my favourite of the lot. It looks positively authentic.

I've taken a few of the drugs mentioned. I'm going to guess Primorge is right about most of the pictures though: there's got to be an element of self conscious contrivance. Short of ODing on some of the drugs (such as Trazodone), their effect isn't going to be consciously noticeable, and I wouldn't think it would make much of a difference in the art. I mean, Trazodone will give you dry mouth and a nasty tasting tongue that makes you feel like you haven't brushed your teeth for a couple of days, but otherwise you'd never know you took it.

Perhaps some enterprising fine artist could do a series of self portraits while on a pub crawl. "Look, here's me after a pint of Guiness; and here's me after two pints of Newcastle Brown Ale."

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PoserPro 2014, PS CS5.5 Ext, Nikon D300. Win 8, i7-4770 @ 3.4 GHz, AMD Radeon 8570, 12 GB RAM.