I don't know that it represents much of a change from V4WM for me.  V4WM bends really well, but honestly, I haven't bothered to convert most of my female V4 characters to weight-mapping because the vast majority of my renders simply don't require it.

I've been playing around with the Genesis figure all day, and I like the fact that it can take the the MATs and hair from older figures.

But clothes?  That's another matter.