Thanks all for your feedback, I have finally bitten the bullet and upgraded to Daz 4.5. As I have a major animation project upcoming and I wanted to take advantedge of the autofits capabilities for transfering morphs for clothing in 4.5

And as a whole everything seems to be working perfectly so far.

The only small thing is I now have a Genesis Starter Essentials in my Smart Content Tab as oppose to just a genesis product folder. I'm finding it easier to load Genesis from the normal content tab as the Genesis Starter Essentials has 200+ icons in it. 

I can't seem to create new Metadata for just Genesis as it was before the upgrade.

But this small issue is nothing compared to some of the new capabilities available.

So thanks again for sharing your experiences with 4.5. It really helped to convince me that this was more than just a an Alpha RC version.