Well with ZBrush and Poser GOZ you can now tweak and fix any V4 bends and unrealistic joints body parts in less than two minutes and make V4 poses look better than any WMV4 or Genesis will ever look in poser alone.

Converting conforming clothing and hair to weight maps is tedious if you have a huge Runtime and the results most of the time not very pretty and the mesh gets altered in some parts too. Copying joints zones is fast but most of the time you will have to deal with pokethrough.

Converting V4 clothes to Genesis is even more tedious and long, needs DS, and the autofit results are also most of the time perfectible and unrealistics specially in the breast area. Clothes also seems wrinkled...

So I guess V4 has still a long life for users like me who have 80% of V4 stuff their runtimes.