Make sure you're running Poser service release 3.1, first off.

See this thread perhaps:

http://www.renderosity.com/mod/forumpro/showthread.php?message_id=3969705&ebot_calc_page#message_3969705

You will possibly need to turn off Irradiance Caching for Indirect Lighting, if what you're rendering is displaying these splotchies...