With few exceptions I do not do gaming so most of my PC use is for Poser.  Instead of a mouse I use a Logitech marble trackball which is optical meaning that you do not have to clean the ball regularly, a real pain on the standard trackball.  You can customise the four buttons which is also useful.

In addition I do have a space navigator which I have been using for almost two years and I would not be without it.  I does work with Poser and can me used the manipulate the cameras and with a click of the button can be use to manipulate limbs on figures for posing.  I cannot get it to work with Silo so I use the cutomise buttons on the trackball and keyboard but it is second best to the navigator. 

I use both for hours at a time and never have a problem with cramp and the like and I also like the fact that the trackball takes up less room on the desk than a mouse.  Having said that I know it is personal taste so this set up would not suit everyone.

 

 

I use Poser 13 on Windows 11 - For Scene set up I use a Geekcom A5 -  Ryzen 9 5900HX, with 64 gig ram and 3 TB  storage, mini PC with final rendering done on normal sized desktop using an AMD Ryzen Threadipper 1950X CPU, Corsair Hydro H100i CPU cooler, 3XS EVGA GTX 1080i SC with 11g Ram, 4 X 16gig Corsair DDR4 Ram and a Corsair RM 100 PSU .   The desktop is in a remote location with rendering done via Queue Manager which gives me a clearer desktop and quieter computer room.