1st: Do you have 'Able to repose in Vue' or Using 'Poser Shaders' enabled? Both of those features require Poser to be running in the background and can eat up a chunk of memory.

2nd: Check the texture size from the Poser resources. SkinVue came to be due to fact that Vue has always had a problem dealing with the humongous textures that can be attached to a Poser figure. Depending on the characters, that many figures could have 2-4 4096x4096x32 bit color textures. Each.

3rd: Are you running a memory checker/cleanup program? Older versions of Poser were....dubioius, shall we say...at cleaning up after themselves. One of little freebie apps that tests your system ram and frees up real estate not in use was the only way shy of shutdown/reboot to make unused texture loads go away.

4th: Are you using a lot of procedurals in your scene? If so, you may not be 'out of memory' so much as 'out of allocation pointer space'.

5th: Are there any other programs running that could be gobbling bytes on you?