I run Poser on my Lenovo i5 system and just the HD3000 graphics - it works "acceptably" with the following caveats:

• The 15.6 inch screen makes reading menus etc. difficult

• I have a three-fan laptop coooer under it, otherwise like has been said the sucker will try to heat the room

• It's maxed out at 8GB, I recommend something more expandable

• Use an external mouse, otherwise yu're going to live in the penthouse of Hotel 
  Frustration (trackpads and 3D are a bad combination) 

Best of luck!