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I would think that some difference is going to be inevitable simply because things look different i.e. natural as opposed to artificial light, lighting types etc. I once spent an uncomfortable few minutes in a parking lot where the lights made my red car look brown. Vue’s not going to make that dramatic a difference but if you get into EZSkin vs. SkinVue plus the render engine differences, I don’t know whether the results will fit within the ‘she just looks different because she’s outdoors’ envelope. Hopefully that makes sense.

I was thinking something similar after posting.  Outdoor vs indoor isn't just lit differently but would likely be used differently in storytelling as well.  A character in casual clothes working indoors probably should look different than that same character running through a thunderstorm.  A reader or viewer has no idea that two different rendering engines were used, they just tend to look for enough similarity to continue believing they are seeing the same characters and objects as before.  I suppose effects artists have to consider similar things when mixing fullscale props shot outside with miniatures shot indoors.