It's not something I've had happen but it worries me with every Flash and IE update. I wouldn't say I'm a Poser addict but I always start Poser after an update to make sure it's not been broken :0

Poser 11 , 180Gb in 8 Runtimes, PaintShop Pro 9
Windows 7 64 bit, Avast AV, Comodo Firewall
Intel Q9550 Quad Core cpu,  16Gb RAM, 250Gb + 250Gb +160Gb HD, GeForce GTX 1060