Most of the morphs are transferred, but not all of them (it depends on how they are made). Morphs based on magnets can be a problem with Copy Morphs

With the morph brush set to a large brush and high impact, fixing poke through is usually a matter of 2 seconds. But when the limbs get close to the body, the morph brush can not figure out which bodyparts the cloth should fit to. That can be done with the restore and pull brushes, but that takes more time to get right

About poses and expressions - without DSON it takes a LOT of time to get the morphs converted and then you have to create the thumbnails as well. With DSON, you still have to load each one fo them and save them seperately. That is a lot of work as well

If you want to stay with a single Poser installation, you can move the DSON folder in addons to a safe place if you want to use Poser without DSON and move it back when you need it. A Poser restart is required however.

So if you are determined to use genesis, you can - with and without DSON. But it is a quite laborous experience.