I have had a 120GB OCZ Agility 3 running Windows 8 for 6 months now. Have run Poser Pro 2012 and 2014 with no problems also. Although, as I have read reports that if SSD's fail it is generally catastrophically, I play safe in having only the main program on the SSD and put all my runtimes on a 2GB Seagate HDD. Easy to backup the SSD onto HHD just in case!

I also run Windows 7 on a 60GB OCZ Petrol SSD (cheaper / lower quality) with no problems. I have an 2.25" caddy in my PC and can change operating systems by simply swapping the SSD's. In my experience there is no reason that Poser, nor any other program, should run any differently on an SSD than on a standard HDD.As you note though, there is not a massive speed increase due to SDD that I noticed, just a little, plus faster starting, plus solid stability.

Other thoughts...

1. Have you checked with OCZ if the SSD firmware is up to date? early firmwares were dodgy I believe.

2. I also have my windows swap and temp files on the HDD as well, to keep junk to a minimum on the SSD. 60GB does not seem a lot of room if especially if you have your runtime on the SSD?  I can't ever remember Poser crashing on me, it's extremely stable. I also have an intel i7 CPU with 16GB of Ram and an ASUS (ATI) EAH6850 GPU

I have had one issue only, to do with shared data when swapping operating systems... A warning here (sorry to digress but it is worth noting this for anyone considering doing it)...  Do not try to share the same hard drive for data between Win 7/XP and Win 8... IT WILL CORRUPT DATA without warning! and it will not be recoverable!  It took me a week or so sorting this one out. I believe this is caused by the newer Windows 8 self healing file system as other web sites have noticed this also, but apparently MS denies this. If you do ever need to do this, give each operating system a separate HDD and hide the opposing one to each system in the windows disk manager. I have had no problems since doing this. It is a pain if you need to share data between the two though!