If you want top end I would recommend you first review the enviroment the computer will be situated in. These monsters will generate a lot of heat so you will need some way of dealing with that , its no good having a super fast PC/Mac if the ambient temperature around the workstation is too high for you to comfortably be able to work. This sounds a bit lame but I know directly of at least one person who built a super fast PC and then sent all the components back because he found it too hot and noisy to use.

The AMD chip is not necessarly faster than the Intel. I'm not an expert but from the reviews read the 8350 will overclock well and make the most of good quality memory but you will pay with much higher electricty bill! The i7 is more efficient and works better if you're looking for a more balanced set-up. Believe some members have already done some real world benchmarks comparing the i7 and FX 8350 which you should be able to find by searching the forum.