When I cleaned my Poser only runtimes some weeks ago I deleted all Daz related files (*.ds, *.dsa, *.dsb and some more exotic older Daz file extentions). Also I delete all .duf files that comes with newer content. Never had any problems with Poser since then so yes, you can delete it safely.

But additionally I still have the original installation files, so should I ever use Daz someday (never say never) I'd still be able to get the deleted files back... ;-)