Unchecking that will remove all the Sub-surface scattering calculations, but that might also minimize the "realistic" look you're going for with Reality.

As I was familiarizing myself with the plug-in, I can't stress enough - read the manual. A lot of programs are easy enough to just jump in & Reality is actually one of them, but there is a LOT of good info in the manual.

Check out the Reality forum over at RDNA. Someone might have come across that same problem already, & if so, Paolo probably gave them some insight on how to correct it. He's really good about answering questions in the forums over there. If there isn't a post with your problem, just create a new topic. I'm certainly no expert, and it makes sense to get answers from the person who wrote the program if you can :)

Poser Pro 2012 SR3 on Win10 x64 w/Reality.
Poser Display Units = inches.