Ok. So in order to use Talk Designer we need two things. An uncompressed single channel audio file, (mono not stereo); and a Viseme map for the character.

For PC users the audio file would be recorded in wav format. For Mac users the format is aiff. Place your audio file in your Poser Content->Runtime->LipSync->Audio Files folder. You could search for them in any location you wish but if you put them here they will show up in the drop down list in Talk Designer.

Viseme Maps: The characters that come with Poser have these maps included. Third party figures may or may not have a viseme map. You can buy software that helps you make these but you can make them yourselves. They are simple xml files. Since TB has one for Pranx we won't bother with this step. Good thing as that is a separate tute all together. Place your viseme xml file in Poser Content->Runtime->LipSync with the ones that come standard for Poser figures. Now your viseme is in the drop down list in Talk Designer. Again, you could search to whatever location you've been storing this file but as you will probably want to use this again it's much easier in the drop down.

With this much done you can now open Poser and load your figure.Open the Talk Designer as shown.