Well, "Just one more thing..." is one of the attractions of Poser, to me. As noted, it does sometimes bite you in the arse instead of providing entertainment.

I always try to remember to save before I do something risky, such as render, run a cloth simulation, or turn IK off. :) Sometimes I forget to save, sometimes the supposedly innocuous little thing I was doing turns out to have been more risky than I expected; but on this occasion, as far as I knew I'd saved a perfectly functioning scene without mishap. How wrong I was...