I try to do as much in the render as possible. So most of the postwork is just fixing things that are easier to postwork than bother to rerender - small bits of pokethrough, wonky bit of texture, weird kinks in hair etc.

Sometimes I add some effects in Photoshop, depends what the final result is supposed to be. But I rarely overpaint anything unless there's some serious problem I need to get rid of.

(It's easier in Vue as a lot of post-render adjustment can be done to the render inside Vue anyway, so any postwork is for Vue renders is usually only a case of fixing any little glitches I hadn't noticed.)