Good points.  Blunder, I mean Blender, is a perfect example of an interface design disaster.  I know the fans point out all the positives about the structure of the application, but what they did there was reinvent the wheel, when the wheel wasn' t broken to begin with.  I think the original designers took some chances, and in the end came up with something that made sense to their brain, but it happens to not make much sense to everyone else.  Andrew Price describes the design flaws best:

http://youtu.be/xYiiD-p2q80

Nuff said bout that. Cinema4D, in my opinion, is the best example of a powerful software designed for usability on all levels.