I use Poser 10 on a 27" iMac with 8 GB of memory, a 3.2 GHz Intel Core i5, and the NVIDIA GeForce GT 755m 1024 MB video card. I find DSON works OK. You have to, as mentioned, turn sub divisions off. I can do a high quality render with a single Genesis 2 figure dressed and with props. I can do scenes with a single Genesis 2 figure and two M4/V4 figures by not using SSS, ray tracing, or casting shadows. I can use all those things in most cases with three M4/V4 figures, so I deduce that Genesis 2 uses more memory. Having DSON in play seems to lead to more frequent crashes during rendering, but that's not a consistent issue. I find that I have frequent difficulty opening a saved scene with a Genesis 2 figure in it, but if I import it into a new scene, DSON usually works OK.  The next time there is a Poser Pro sale, I may buy it to find out whether the 32 bit memory limit plays a role. For me, the bottom line is that DSON is good enough to use, and the other things I prefer about Poser make it worth not using DAZ figures in their native environment. I hope that helps.