I don't think it will. I'm using Windows 10 in Parallels. It's no different that using Windows on a dedicated machine, but I can also move to that mode also to test it out. I just use the Mac portion to open the text files and file explorer (called Finder on the Mac). I could have also used Windows apps to do those items, but it is slower being in a virtual space.

Also, I've noticed that gravity is a bit of an issue, especially if I do the static draping. If I leave it at 40, the cloth item will pull off the model and there always seems to be some distortion around the breast portion of the garment. I plan to play with it some more tomorrow.