For Poser content, I work with Zbrush-Modo-Photoshop. Zilo is an excellent alternative to Modo for a lot of things. From a sculpting point of view, I have not really found something (that for me) gives me the organic workflow that replaces Zbrush. Zbrush has a good workflow with Poser Pro for creating morphs. Lots of good image editors are out there--I'm an old hand with Photoshop, so I stick with that. -K