@Cyberdene: It would help to know what version of Poser you're using. If you have Poser 9+ and you need to use V4 for the work you're doing, then I would also suggest V4WM. But ultimately it doesn't matter which figure you use, whether it is one of the weightmapped figures or one of the Genesis figures, corrections are always needed to get closer to realism as none of them have realistic bending. If you're doing still renders then you can export the posed figure to zbrush and sculpt the necessary corrections yourself. It's not that difficult if you have proper reference images. If you don't have ZBrush I think blender can be used in place of it.

If you're doing animations then it gets a bit trickier as you're going to need to create custom JCMs. Magnets also help.