Yes! Absolutely! 'Cheating' on Vicky Fourpointtwoplusplus is unthinkable. There's also the matter of her sizable wardrobe which I've invested in over the years. If my real world wife was as high maintenance as Vicky, I'd be a pauper. Despite the hysterical arm waving of the Daz fanboys, Vicky still works (and looks) great. Heck, even Vicky Three can hold her own id one has the skills. In another forum we have a Vicky Three thread on the go and some of the renders are just as good (if not better) than some of the Genesis Three stuff I've seen.
A development to watch is the upcoming 'Project E' from the amazingly talented Erogenesis. She will be compatible with Vicky Four characters and clothes and will...well follow her story on CGBytes. If you're going to make clothes for her, then I'd suggest that you fill in the gaps in her wardrobe and not cover the same ground. She has a million bikinis and skimpy outfits. A modern woman like Vicky needs a variety of business outfits. How about some good formal outfits. So many of the offerings are 'goofy' and don't really resemble clothing that a real person would wear. Fashion websites are full of beautiful gowns that can provide some inspiration.