I've never personally found a pen stylus useful for more than 10% of my needs in a 3d package. Of course, if you do a lot of sculpting in applications such as 3dCoat or Zbrush, the variable stylus sensitivity settings can provide a level of control unmatched by a mouse or any other navigation device. As for standard polygonal modeling and the bulk of my overall workflow, I prefer a 3Dconnexion SpaceNavigator or just a standard mouse; much more predictable control and more options for 90% of your 3d creation and animation needs.

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