OK. Studio 4.10 is installed. So far so good. First test with Genesis male 2 and Grantham jacket: It works, materials are there. No issue there, it renders fine. Save the scene. Close Studio. Restart Studio and load saved file. Materials are still there... and render works.

I'll do some more test but I'm afraid I'll need more information to solve the reported issue. The best would be a case involving only some product I don't have to buy , something shipped in with studio.