I had a quick look at the slideshow and it has some good tips for dealing with the Render settings tab.

It may be that you are trying to include too much in a single preset as things like exposure will vary depending on the amount of light in the scene. Whereas optimisation tends to be more useful across different types of scenes. It may take a bit more time but you can save out specified groups of settings so that the saved preset only effects the more relevant settings for that preset. For example you can just save out a preset which includes the settings for Optimisation and Filtering only and call it something like Preview quality, Medium or High quality depending on the setup. The settings for Tone Mapping and Environment tend to be a lot more scene specific with Tone mapping being pretty close to film and camera settings. So alternatively you could set the Tone map options for things like indoors or outdoors and save a preset that includes the tone mapping and possibly environment settings only.