I dont use a lot of faux-line post work on my comic strip — I tried it a few times and found the results less than convincing. It is possible to emulate pencil and ink, but man it's a lot of work: you might as well just say screw it and draw it all out by hand and be done with it.

So instead, I opt for either a simple 2x2 or 2x3 panel layout... or else something more extravagant like this, where the colours are used to define who's saying what and move the eye down the page. These are certainly a lot more fun to do, and they're all pretty well impromptu creations: when I"m putting one of these together, everything — the writing, the layout, the hopelessly overworked finish — is all done to whim of the moment. And it usually results in things I would consider my better work.

docandraider.com -- the collected cartoons of Doc and Raider