I have a machine running on 32 RAM and though I haven't tried anything extreme yet I haven't noticed any slowing down so far. I should try a render on extreme settings and with 30 pixels samples. Took nearly a day on my previous machine. Also, on my previous 16 RAM PC if a render was in progress it would claim my whole computer. Nothing else worked properly : videos, etc ... Now I can render and meanwhile run multiple other programs too.

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