I only use poser so can't talk about blender, and no-one knows what poser 12 will be.

However the problems I see with the system you have described is that with AMD graphics you will not be able to use gpu rendering in superfly, and the cpu only has 4 cores without hyperthreading (or whatever AMD calls it, this is what allows 4 cores to act like 8 cores) so cpu rendering will not be particularly fast, so personally this is not a machine I would choose for poser