Well i cheat sometimes by using surface maps. But i prefer to make my own brushes for the pores and look at the pores of my reference photos. You can sculpt a pore map iin zbrush or a comparable program and use that as an alpha/brush. This way in poser or daz studio you wont get harsh lines on the skin. Also you have to take in to account poser and studio use tangent space normals and they are calculated differently in both programs.

I think substance painter uses the GPU to run right? and zbrush doesnt. so it is not so important to have 4 gb for instance on your videocard. But a lot of ram is paramount for this.