To the point of geometry setup and renders, I think that's always a concern when transferring geometry from program to program. Nonplanar quads can be troublesome, as can unbeveled sharp edges. Mark Sharp is a nice way around it, but you can't rely on that to transfer or work as expected in the target program. Ideally, I suppose we want the beautiful mesh made of evenly-spaced planar quads. But I've seen plenty of models that are kind of crap when you look at the wireframe. Yet, they render well enough. For giggles, I've applied a subdivide modifier to some of them. That broke them. Building models for subdivision has its own challenges.

Blender gets even weirder with its ability to handle n-gons all day long. Blender sort of invites people to make ugly meshes that look great when rendered. Reminds me of people who draw poorly but render beautifully. Since you don't usually see their line drawings, no one cares.