For those that don't have PML that is a very handy script, from my understanding it works in 12 too. ADP is very generous, he's been quite helpful to me and many others. I haven't really noticed any downsides to not scaling up, at least for the low frequency sculpting I do in Blender. Retopo is another story. I will say that in Mudbox it's an absolute necessity, like 2000% lol.

Thanks for your suggestions RedPhantom