1. You are aware Poser12 supports all of SciPy (see SciPy.org), right? There's quite some stuff there that may be useful.  

2. Non-manifold meshes are quite common in clothing models. Think of ruffles and hems. In conforming garments you do not need structural integrity, but in dynamic garments it is essential. In figures they may appear in eyelashes etc. You could consider the non-manifold edges as free edges