Digging further, the pathway that should be as follows: C:\Users\Users Name\AppData\Local\VirtualStore\Program Files\MyApplication.  This is based on Windows Vista when UAC and Virtualization were first implemented.  The pathways may have changed since then due to version updates.  But at least this is a starting point.  Again, I can't pursue this further because I don't store anything original content in the Program Files folder.

To find out more about it, Google Microsoft Virtualization and UAC.