It looks like Lindows is simply a Linux release with some additional goodies based on the work done under a project called WINE.

WINE is an OK tool for running some Windows software under Linux, but it will never be current with Microsoft technology and it is never intended to be a total replacement.

In short, I seriously doubt Lindows will be a real alternative. If for no other reason than getting tech support for your software if you are running it will be almost impossible.