My best suggestion is to go into General Preferences and on the Document tab, set launch behavior to 'Launch to factory scene' and proceed to the Interface tab and set launch behavior' also to 'Launch to factory state'.   Close the panel and reboot Poser.  Afterward, reset the General Preferences back to your previously selected state.  Unfortunately, If you customized the UI, you will need to manually restore the panels where you want them.  Use the UI Dots in each room to preserve your setup, and prevent any accidental panel movements by unchecking 'Drag-Docking Enabled'.  I spread my workspace over 2 monitors so I use the Docked/Floating features exclusively to rearrange my panels.