Cycles is, as we know, a render engine that tries to take physical conditions into account as much as possible (PBR = Pysical Based Renderer). This was not the case with previous render engines in Poser. Which means that the usual materials from the "good old days" have to be reworked.
An important aspect to consider today is the skin structure (the physical: roughness, unevenness). First and foremost: pores. For young people, these are very small, sometimes barely visible. With increasing age, this changes massively. These pores change how light is reflected from the skin. And not a little.
The Voronoi shader can help to simulate this (it breaks the highlights, even if the pores themselves are too small to be noticeable). This gives skin its typical character.

Even a simple implementation can do wonders for an image. Two images will illustrate this: First the original material of Antonia:

Here with the material supplemented with a Voronoi shader (same light condition):

First, I took the liberty of converting the original bump map to a normal map using a Cycles shader. This frees the port for the bumpmap in "PhysicalSurface" to directly link the Voronoi shader there. The latter has a negative scale value to invert the effect. Last but not least I changed the original bumpmap intensity from 0.0025 to 0.00125. In addition, it may make sense to reduce the "Roughness" intensity (0.4 for example).

Play with the values, There is no "One for All" setting. Depending on geometry, light, textures, personal taste etc. the necessary values can change. And please, please consider the age. A teenager with fat pores is simply an insult to the eye.

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