I have just upgraded to Monterey on an Intel Mac Mini and Poser 11 is running as it did on Catalina, with two (so far) annoying exceptions.

1: The window greys out when calculating dynamic clothing, which means you can't see what is happening until the final frame.

2: In Firefly, the window greys out as soon as you click on it to do an area render, making it difficult to be precise with the area of the render.