Last I heard, the only Poser 12 problem with Windows 7 is if you need any paid Poser 12 scripts, as purchased via the Renderosity store. Apparently Windows 7 doesn't have the ability to lock them down on your PC? Whereas the other later Windows OS's do. This situation may have changed since I looked at the problem, but I've not heard that it has changed.

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Learn the Secrets of Poser 11 and Line-art Filters.