I know it may not help and its only a thought because I'm still on P10. I'm on Windows 11 now, a move I made when Apple moved to 64 bit only. When I was using my Mac I did have a similar problem with Poser dials freezing when I tried to move them with the mouse and I traced it back to the Magic Mouse I was trying to use. I think it was something to do with the Bluetooth connection. I had no problems at all once I went to a wired mouse. If memory serves I got myself a Razer Taipan and installed the Razer Synapse software. I never tried a wireless mouse. 

Maybe its something to try.