Many zones can be useful for certain types of render passes, which are then used for (re)coloring on a comic-book page. For instance, the free "More Poser 12 helper scripts" set on ShareCG has a Poser script to set all ToonIDs to a random high color (i.e. relatively bright, compared to the dull and dark defaults).

The scene can then be output as a Firefly "Auxiliary" render of the ToonIDs, to then be used in Photoshop when paint-bucketing in some consistent cross-panel comic-book colours. The line-art would be separate in Photoshop, laid on top of the color flats with the white knocked out via an Action.

Of course, the ideal is to have just enough PoserSurface zones seen in a render, but not too many. But if the clothing is intricate, then having many zones may be useful for postwork. Such as when using render passes that allow for fine selections (e.g. "select by colour" the 24 brass buttons on a steampunk outfit) in Photoshop.

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Learn the Secrets of Poser 11 and Line-art Filters.