You need to reconfigure the installation options with Poser so that your content will be placed on your secondary drive.  The option will be available when you reinstall Poser.  Initially, all your content should be directed to the Poser 11 Content folder and you must tell the Poser installer where you want that folder to be installed (second drive).  Once that is established, your Download and Purchases folders will also be created in that location.  Any other additional runtimes can either be created or moved to the new drive and relinked to the Poser Library.

Content folders need to be linked to DIM manually and then be selected manually for proper installation depending on how you organized your content files.