I don't know for Poser5 but I had tested this on my old PC (died 2 months ago): an installed Poser6 folder can be copied and run from any new location.

𝒫𝒽𝓎𝓁

---

(っ◔◡◔)っ

👿 Win11 on i9-13900K@5GHz, 64GB, RoG Strix B760F Gamng, Asus Tuf Gaming RTX 4070 OC Edition, 1 TB SSD, 6+4+8TB HD
👿 Mac Mini M2, Sequoia 15.2, 16GB, 500GB SSD
👿 Nas 10TB
👿 Poser 13 and soon 14 ❤️