When you install Poser this should apply to Poser's 12-14, I know it works with 13 and 14 as I have done it at least 100 plus times in the past 4 years.  When you get the installer it will ask for where you want to place your Poser program. It will open up a dialog box and ask you to Select Destination Location and it will be prefilled with where to place the program.  The very first time it will probably say some like C:\Programs\Poser\*.* (it has been a very long time since I let it install to the C drive.  I normally tell it to install to E:\Poser\Poser 14 as that is what normally fills in after the very first install of a new version.  Since I never install over a prior version (saves time deleting) I just make sure Poser is shutdown and rename the Poser program folder something like ZPoser14_0_0148 (the current version that i am running) and let the installer place the new version in the Poser 14 folder which it creates since the old folder was renamed. One you have told it where to put the program then you get the choice of where to put the runtime.  The default is Shared documents directory.  You want the bottom one Other Location. Check that and on the next screen it will always come up with "C:\Users\Public\Documents\Poser 14 Content"  here you have to make sure not to click through or it will mess up your install.  Click the Browse button and it will bring up the picker choose the folder above where you want the content to go (in my case it is E:\Poser Content\) choose that it and it will fill in with "E:\Poser Content\Poser 14 Content".  Then click on through until the program installs.

As long as you don't save anything to the default Poser 14 runtime you can do this everyday and never worry about losing any content.

The added benefit is that you have a prior copy of the program that you can run by going into the renamed folder an double clicking the Poser progarm icon.

Poser 5, 6, 7, 8, Poser Pro 9 (2012), 10 (2014), 11, 12, 13, 14