If the program can save an Wavefront OBJ file (.obj) you should be able to make clothes. For the details of the matter check out some of the great tutorials that are in the tutorials section. As for programs you will need to work with the files get BBEdit (BBEdit lite is a free and powerful text editing program - www.barebones.com), Macconverter 1.1.4(www.soft-rabbit.com),and UV Mapper (for textures -www.uvmapper.com). As far as making changes to a file and poser not recognizing it, anytime you make a change in a file just drag and drop it on macconverter...problem solved (if you are working in BBEdit it's even easier because you can save the changes and BBEdit does not change the kind of file that it is so Poser still recognizes it). I have found the Mac a wonderful platform for poser, so good luck and enjoy.