Ok your best bet would be to print from either Freehand or Illustrator. With either one, you can get very exact for printing. Speaking from personal experience, photoshop can get wonky sometimes when printing, even with exact settings. Standard commercial printing is 300 dpi. A lot of commercial shops refuse to print any higher. As for creation, create as high as you want. If you look at The Grudge in my gallery, thats a 600 ppi image. Reason I made it so large was just in case I wanted to enlarge it later on, and because I wanted to put as much detail into it as I wanted to. Anything less than 150ppi aint too shit hot. Anything above is fine. Working at 1200 ppi is fine, and not overkill if you wanna put that much effort and detail into it, but printing over 300 dpi won't make a huge difference (though it is noticable on closer inspection). also, just in case, ppi= pixels per inch, for on screen. dpi= dots per inch for printing, and each dot doesn't actually replicate each pixel.